More recently, Alfie got the bad news that the cancer had not all been removed, meaning that he would be forced to undergo additional treatment.
With Kat Slater (Jessie Wallace) believing that Alfie had been given the all clear, she laid into him for pulling a disappearing act, only to be left gobsmacked when he revealed the truth.
Kat and Alfie have always had a close bond, even despite their rocky relationships.
For this reason, Alfie is silently pleased when Kat agrees to accompany him to the hospital for his first hormone injection.
Kat has not been Alfie’s only supporter, as Linda Carter (Kellie Bright) has stood by his side during this difficult time, refusing to let him go through his prostatectomy alone.
But with Kat and Alfie’s history, could they start to develop feelings for each other once more during this emotionally charged time?
What Kat doesn’t know is that Alfie is harbouring a huge secret about Kat’s husband Phil Mitchell (Steve McFadden).
After a heated row during which Kat admonished Phil for keeping Alfie’s cancer scare from her, Phil slept with Emma Harding (Patsy Kensit), just days before his wedding.
It wasn’t long before Alfie found out, and battled with whether or not to tell Kat, before ultimately deciding against it, agreeing with Phil to keep his secret as long as Phil kept his true cancer results a secret in return.
But this is EastEnders, and there is every chance that Phil’s secret could come out sooner rather than later, and with a dead body expected to hit the Queen Vic floor on Christmas day, Phil’s future is not guaranteed.
Could Kat be swayed back to Alfie’s arms?